Endoscopic Submucosal Dissection, Procedure, Performance, Post-Procedure & More

Endoscopic Submucosal Dissection

Endoscopic Submucosal Dissection (ESD) is basically a surgical procedure that doctors use to remove early-stage tumours and abnormal tissues from the gastrointestinal tract.

Unlike other methods for the same purpose, ESD is used to remove the larger lesions, which is beneficial for long-term patient health and positive outcomes.

The Procedure’s Significance of Endoscopic Submucosal Dissection

There is a huge advantage that ESD has over older techniques, such as endoscopic mucosal resection, the precision and efficiency that it provides in removing abnormal growths.

This is super useful when dealing with precancerous conditions, where accurate diagnosis and complete removal are essential. ESD is a game-changer for treating early-stage gastrointestinal cancers, offering less invasive options for patients.

Endoscopic Submucosal Dissection, Procedure, Performance, Post-Procedure & More

How is Endoscopic Submucosal Dissection Performed?

  • Endoscope Insertion: A specialized endoscope is first inserted through the mouth or other body openings to reach the target area.
  • Camera Guide: The endoscope that is being used has a camera and light source, which allow the medical professional to visualize the affected area.
  • Mucosal Incision: A small cut is made in the mucosa, the inner lining of the gastrointestinal tract.
  • Submucosal Dissection: The endoscope is then used to carefully dissect the layer beneath the mucosa, known as the submucosa.
  • Lesion Removal: The abnormal tissue or lesion is isolated and removed in one piece, if possible.
  • Tissue Analysis: The extracted tissue is sent to a lab for further examination to confirm the diagnosis.

Post-Procedure Care of Endoscopic Submucosal Dissection

Following an ESD, patients are usually kept under observation to monitor for complications like bleeding or any other complication that might or might not occur.

The removed tissue is sent for pathological analysis to confirm the diagnosis and evaluate the effectiveness of the treatment.

Patients can typically resume regular activities within a few days but should follow all aftercare instructions carefully.


With its high precision and minimally invasive nature, ESD is becoming a preferred method for treating various gastrointestinal conditions. So here you get a complete guide on what is Endoscopic submucosal dissection.

Dr. Amit Agarwal
Director & Gastroenterologist Consultant
Agarwal Gastrocare Center Indore

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